Chih-Sheng Lin 林志生
Professor
BioMedical Engineering Laboratory
Department of Biological Science and Technology
National Chiao Tung University
75 Po-Ai Street, Hsinchu 30068, TAIWAN
Tel: 886-3-5712121 ext. 56954 or 56940
Fax: 886-3-5729288
e-mail: lincs@mail.nctu.edu.tw
2019/01-presnt
Associate Editor of Journal Food Safety
2018/10-2019/1
Vice-Dean of the College of Biological Science and Technology
2018/10-2019/7
Chairman, MD-PhD Program (Biomedical Science and Technology Ph.D Program)
2012/8-2013/2
Vice-Dean of Academic Affairs
2012/8-2013/2
Director, Center for Teaching and Learning Development
2007/8-present
Professor of the Department of Biological Science and Technology, National ChiaoTung University
2007/8-2009/9
Chairman of the Department of Biological Science and Technology, National ChiaoTung University
2006/10-2015/8
Graduated faculty, Department of Human Nutrition and Food Science, University of Maine, USA
2006/7-2006/9
Scholar visitor at Department of Human Nutrition and Food Science, University of Maine, USA
2003/8-2007/7
Associate Professor at National Chiao TungUniversity
2001/8-2003/7
Assistant Professor at National Chiao TungUniversity
2001/1-2001/6
Visiting researcher at the NationalLaboratory Animal Center
1998/8-2001/7
Associate Researcher at Pig Research Institute Taiwan
2011-2020: 國立交通大學 研究傑出彈性薪資暨科技部獎勵
2017: 中央研究院南部育成中心所舉辦「運用新穎生物科技搶攻循環經濟商機暨技術交流研討會」,題目:『以藻類固碳與生物精煉平台進行二氧化碳高值化利用及商業化技術開發』。
2016: 代表「減碳淨煤主軸中心」參展『第二期能源國家型科技計畫總期程期中成果展』
2016: 2016 東元「 Green Tech」國際創意競賽,獲得「大會特色獎 ─ LEKO低碳技術獎」
2016: 食品工業發展研究所主辦之「固碳與產油微藻資源應用研討會」,演講題目:『結合廢水和廢氣利用於微藻固碳養殖與生產微藻生物質』
2016: 與農業科技研究院聯合參加『2016台灣生物科技大展』
2016: 科技部產學媒合會(台中),主講『藻到好價值』,即聯合金屬中心「微藻破壁技術」及「低溫萃取技術」,研發微藻轉化成生質燃料的關鍵技術,有助於永續能源產業發展。
2016: 台北國際發明暨技術交易展之「能源國家型科技計劃之期中成果展」。
2015: 代表第二期能源國家型科技計畫參展『台灣國際綠色產業展』
2015: 全國工業節能創意實作競賽『廢水固碳再利用於微藻養殖模組』獲選『優選』
2014: 化工傑作獎 (Outstanding Chemical Engineering Article of the Year) from台灣化學工程學會 (Taiwan Institute Chemical Engineers)
2010-2016: Outstanding Research Award from the National Chiao Tung University
2011: Excellent poster award in the 16th Conference on Biochemical Engineering, Taipei, Taiwan
2010: Excellent poster award in the 15th Conference on Biochemical Engineering, Tainan, Taiwan
2010: Excellent oral award in the 15th Conference on Biochemical Engineering, Tainan, Taiwan
2009: The 4th prize in the IFT (conference of International Food Technology) conference award, Anaheim, USA (國際食品科技研討會)
2009: Finalist. CREATed in TAIWAN 4th (宏碁/天下雜誌-龍騰微笑競賽)
2009: Honorable Prize, 2009 Biotechnology R&D Creative Application Competition from the Industrial Development Bureau, Ministry of Economic Affairs (經濟部工業局-生物技術研發成果創意應用競賽)
2009: Honorable Prize, The 14th Conference on Biochemical Engineering. Taichung, Taiwan (生化工程研討會)
2008: National Innovation Award (3rd Prize) from the Institute for Biotechnology and Medicine Industry (國家生技醫療產業策進會-國家新創獎)
2008: The Gold medal. 2008 Star of Future Biotechnology at National ChiaoTung University, Taiwan
2008: Silver Medal, 2008 Biotechnology R&D Creative Application Competition from the Industrial Development Bureau, Ministry of Economic Affairs (經濟部工業局-生物技術研發成果創意應用競賽)
2008: The 3rd Prize, the IFT (International Food Technology) conference poster award, New Orleans, USA, 2008 (國際食品科技研討會)
2007-2010: NSC grant for the potential and outstanding scholars (國科會傑出學者養成計畫)
2007: National Innovation Award (3rd Prize) from the Institute for Biotechnology and Medicine Industry (國家生技醫療產業策進會-國家新創獎)
- Lin YC, Chen TY, Chien WC, Chung CH, Chang HA, Kao YC, Tsai CS, Lin CS, Tzeng NS. 2020. Stimulants associated with reduced risk of hospitalization for motor vehicle accident injury in patients with obstructive sleep apnea-a nationwide cohort study. BMC Pulmonary Medicine 20(1):28.
- Lin CW, Chang CC, Chen HT, Chen YJ, Lin CS, Hsu HC, Tsou HK. 2020. 3D Real-time image-guided navigation spine corpectomy with ultrasonic bone cutter: Technical Note. World Neurosurgery 135:197-204.
- Lin CY, Chang CC, Tseng C, Chen YJ, Tsai CH, Lo YS, Hsiao PH, Tsou HK, Lin CS, Chen HT. 2020. Seizure After Percutaneous Endoscopic Surgery-Incidence, Risk Factors, Prevention, and Management. World Neurosurg. 138:411-417.
- Yu KL, Chen WH, Sheen HK, Chang JS, Lin CS, Ong HC, Show PL, Ng EP, Ling TC. 2020. Production of microalgal biochar and reducing sugar using wet torrefaction with microwave-assisted heating and acid hydrolysis pretreatment. Renewable Energy 156:349-360.
- Yu KL, Chen WH, Sheen HK, Chang JS, Lin CS, Ong HC, Show PL, Ling TC. 2020. Bioethanol production from acid pretreated microalgal hydrolysate using microwave-assisted heating wet torrefaction. Fuel 279(11):118435.
- Sun YL, Kuo CM, Lu CL, Lin CS*. 2020. Review of recent advances in improved lateral flow immunoassay for the detection of pathogenic Escherichia coli O157:H7 in foods. Journal of Food Safety. (Accepted)
- Hsieh WY, Chang TH, Chang HF, Chuang WH, Lu LC, Yang CW, Lin CS*, Chang CC. 2019. Renal chymase-dependent pathway for angiotensin II formation mediated acute kidney injury in a mouse model of aristolochic acid I-induced acute nephropathy. PLoS One. 14(1):e0210656.
- Quintela IA, de los Reyes BG, Lin CS, Wu VCH. 2019. Simultaneous colorimetric detection of a variety of Salmonella spp. in food and environmental samples by optical biosensing using oligonucleotide-gold nanoparticles. Frontiers in Microbiology 10:1138. doi: 10.3389/fmicb.2019.01138
- Lin CY, Chang CC, Chen YJ, Tsai CH, Tsou HK, Lin CS, Ho MW, Chen HT, Hsu HC. 2019. New strategy for minimally invasive endoscopic surgery to treat infectious spondylodiscitis in the thoracolumbar Spine. Pain Physician 22:281-293.
- Lin YC, Tsai CS, Li IH, Tsai YT, Huang TY, Lee KF, Lin CS, Shih JH, Kao LT. 2019. Transplant Recipients Using Tacrolimus Had Higher Utilization of Healthcare Services Than Those Receiving Cyclosporine in Taiwan. Front Pharmacol. 19(10):1074.
- Lin CW, Chang CC, Chen HT, Chen YJ, Lin CS, Hsu HC, Tsou HK. 2019. 3D Real-Time Image-Guided Navigation Spine Corpectomy with Ultrasonic Bone Cutter: Technical Note. World Neurosurg. pii: S1878-8750(19)32824-4.
- Chen PC, Chang CC, Chen HT, Lin CY, Ho TY, Chen YJ, Tsai CH, Tsou HK, Lin CS, Chen YW, Hsu HC. 2019. The Accuracy of 3D Printing Assistance in the Spinal Deformity Surgery. Biomed Res Int. 2019:7196528.
- Lin CI, Tsai CH, Sun YL, Hsieh WY, Lin YC, Chen CY, Lin CS*. 2018. Instillation of particulate matter 2.5 induced acute lung injury and attenuated the injury recovery in ACE2 knockout mice. International Journal of Biological Sciences 14:253-265. doi:10.7150/ijbs.23489.
- Huang CY, Hsieh JS, Chuang WH, Lin CS, Hsieh WY. 2018. The effects of angiotensin converting enzyme II (ACE2) in bleomycin-induced pulmonary injury. Thoracic Medicine 33:50-62.
- Kuo CM, Jian JF, Sun YL, Lin TH, Yang YC, Zhang WX, Chang HF, Lai JT, Chang JS, Lin CS*. 2018. An efficient PBRs/Raceway circulating system combined with alkaline-CO2 capturing medium for microalgal cultivation. Bioresource Technology 266: 398-406.
- Cho CC, Hsieh WY, Tsai CH, Chen CY, Chang HF, Lin CS*. 2018. In vitro and in vivo experimental studies of pm2.5 on diseases progression. International Journal Environmental Research and Public Health. 15(7). pii: E1380. doi: 10.3390/ijerph15071380.
- Chen CY, Wu VC, Lin CJ, Lin CS, Pan CF, Chen HH, Lin YF, Huang TM, Chen L, Wu CJ; National Taiwan University Study Group on Acute Renal Failure. 2018. Improvement in Mortality and End-Stage Renal Disease in Patients With Type 2 Diabetes After Acute Kidney Injury Who Are Prescribed Dipeptidyl Peptidase-4 Inhibitors. Mayo Clin Proc. 93(12):1760-1774.
- Chang HF, Sun YL, Yeh FY, Tseng IH, Chang CC, Lin CS*. 2018. Detection of chymase activity using the specific peptide probe conjugated onto gold nanoparticles. RSC Advances 8:29013 – 29021.
- Chen CY, Lin CJ, Lin CS, Sun FJ, Pan CF, Chen HH, Wu CJ. 2017. The prevalence and association of chronic kidney disease and diabetes in liver cirrhosis using different estimated glomerular filtration rate equation. Oncotarget 9:2236-2248. doi: 10.18632/oncotarget.23368. (IF=5.168, 44/217 in ONCOLOGY)
- Wu CJ, Chen CY, Lai TS, Wu PC, Chuang CK, Sun FJ, Liu HL, Chen HH, Yeh HI, Lin CS, Lin CJ. 2017. The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease. Oncotarget 8:83030-83037. doi: 10.18632/oncotarget.18789. (IF=5.168, 44/217 in ONCOLOGY)
- Yang CW, Lu LC, Chang CC, Cho CC, Hsieh WY, Tsai CH, Lin YC, Lin CS*. 2017. Imbalanced plasma ACE and ACE2 level in the uremic patients with cardiovascular diseases and its change during a single hemodialysis session. Renal Failure 39:719-728.
- Lee TM, Tseng YF, Cheng CL, Chen YC, Lin CS, Su HY, Chow TJ, Chen CY, Chang JS. 2017. Characterization of a heat-tolerant Chlorella sp. GD mutant with enhanced photosynthetic CO2 fixation efficiency and its implication as lactic acid fermentation feedstock. Biotechnology for Biofuels 10:214. (IF=5.203, 19/160 in BIOTECHNOLOGY & APPLIED MICROBIOLOGY)
- Yang YC, Jian JF, Kuo CM, Zhang WX, Lin CS*. 2017. Biomass and lipid production of Chlorella sp. using municipal wastewater under semi-continuous cultivation. International Proceedings of Chemical, Biological and Environmental Engineering 101: 18-25. (non-SCI)
- Ho SH, Chiu SY, Kao CY, Chen TY, Chang YB, Chang JS, Lin CS. 2017. Ferrofluid-assisted rapid and directional harvesting of marine microalgal Chlorella sp. used for biodiesel production. Bioresource Technology doi: 10.1016/j.biortech.2017.05.110. [Epub ahead of print] (IF=5.651, 14/158 in BIOTECHNOLOGY & APPLIED MICROBIOLOGY)
- Kuo CM, Lin TH, Yang YC, Zhang WX, Lai JT, Wu HT, Chang JS, Lin CS*. 2017. Ability of an alkali-tolerant mutant strain of the microalga Chlorella sp. AT1 to capture carbon dioxide for increasing carbon dioxide utilization efficiency. Bioresource Technology 244:243-251. (IF=5.651, 14/158 in BIOTECHNOLOGY & APPLIED MICROBIOLOGY)
- Kuo CM, Chang YB, Lin TH, Yang YC, Zhang WX, Lai JT, Wu HT, Lin CS*. 2017. Effects of a protein-enriched crude lysate from Chlorella sp. against acetaminophen-induced liver injury. IOSR Journal of Biotechnology and Biochemistry 3(1):82-88. (non-SCI)
- Sun YL, Wu HT, Lin CS. 2016. Direct colorimetric detection of canine distemper virus by RT-PCR combined with gold nanoparticles. IOSR Journal of Biotechnology and Biochemistry 2(6):69-74. (non-SCI)
- Kuo CM, Jian JF, Lin TH, Chang YB, Wan XH, Lai JT, Chang JS, Lin CS*. 2016. Simultaneous microalgal biomass production and CO2 fixation by cultivating Chlorella sp. GD with aquaculture wastewater and boiler flue gas. Bioresource Technology 221:241-250. (IF=4.917, 1/14 in AGRICULTURAL ENGINEERING)
- Hung YH, Hsieh WY, Hsieh JS, Liu FC, Tsai CH, Lu LC, Huang CY, Wu CL, Lin CS*. 2016. Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout Mice. International Journal of Biological Sciences 12:454-65. (IF=3.982, 78/289 in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Chuang SH, Lin CS. 2016. Single-incision laparoscopic surgery for biliary tract disease. World Journal Gastroenterology 22:736-747. (IF=2.787, 38/79 in GASTROENTEROLOGY & HEPATOLOGY)
- Lu LC, Yang CW, Hsieh WY, Chuang WH, Lin YC, Lin CS*. 2016. Decreases in plasma MMP-2/TIMP-2 and MMP-9/TIMP-1 ratios in uremic patients during hemodialysis. Clinical and Experimental Nephrology 2015 Dec 28. (IF=1.945, 34/77 in UROLOGY & NEPHROLOGY)
- Kuo CM, Chen TY, Lin TH, Kao CY, Lai JT, Chang JS, Lin CS*. 2015. Cultivation of Chlorella sp. GD using piggery wastewater for biomass and lipid production. Bioresource Technology 194:326-333. (IF=4.494, 1/12 in AGRICULTURAL ENGINEERING)
- Chiu SY, Kao CY, Chen TY, Chang YB, Kuo CM, Lin CS*. 2015. Cultivation of microalgal Chlorella for biomass and lipid production using wastewater as nutrient resource.Bioresource Technology 184:179-189. (IF=4.494, 1/12 in AGRICULTURAL ENGINEERING)
- Quintela IA, de los Reyes BG, Lin CS, Wu VCH. Simultaneous Direct Detection of Various Shiga-toxin Producing Escherichia coli (STEC) Strains by opticalbiosensing with oligonucleotide-functionalized gold nanoparticles. Nanoscale 7:2417-2426. (IF=7.394, 21/259 in MATERIALS SCIENCE, MULTIDISCIPLINARY)
- Huang CH, Chang CC, Kuo CL, Huang CS, Lin CS*, Liu CS. 2015. Decrease in plasma cyclophilin a concentration at 1 month after myocardial infarction predicts better left ventricular performance and synchronicity at 6 months: A pilot study in patients with ST elevation myocardial infarction. International Journal of Biological Sciences 11: 38-47. doi: 10.7150/ijbs.10271 (IF=4.509, 63/289 in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Yang WJ, Hwang YC, Lin CS, Hwu YM, Lee RK, Hsiao SY. 2015. Embryonic early-cleavage rate is decreased with aging in GnRH agonist but not inantagonist protocols. Journal of Assisted Reproduction and Genetics 32:789-795. (IF=1.718, 42/79 in OBSTETRICS & GYNECOLOGY)
- Yang WJ, Liu FC, Hsieh JS, Chen CH, Hsiao SY, Lin CS*. 2015. Matrix metalloproteinase 2 level in human follicular fluid is a reliable marker of human oocyte maturation in in vitro fertilization and intracytoplasmic sperm injection cycles. Reproductive Biology and Endocrinology 13:102. (doi: 10.1186/s12958-015-0099-8) (IF=2.226, 18/30 in REPRODUCTIVE BIOLOGY)
- Chuang SH, Yang WJ, Chang CM, Yeh FY, Lin CS, Yeh MC. 2015. Is routine single-incision laparoscopic cholecystectomy feasible? A retrospective observational study. American Journal of Surgery 210:315-321. (IF=2.291, 59/198 in SURGERY)
- Chuang SH, Chen PH, Chang CM, Tsai YF, Lin CS*. 2014. Single-incision laparoscopic common bile duct exploration with conventional instruments: an innovative technique and a comparative study. Journal of Gastrointestinal Surgery 18:737-743. (IF=2.391, 51/202 inSURGERY)
- Huang CH, Chiu PF, Lin CS, Chang CH, Chang CC. 2014. Increasing Dyssynchrony during 3-dimensionalDobutamine Stress Echocardiography Correlated with the 2-year Worsening Echocardiography Findings in Continuous Ambulatory Peritoneal Dialysis Patients. Experimental and Clinical Cardiology 20:1148-1168. (IF=0.758, 111/125 in CARDIAC & CARDIOVASCULAR SYSTEMS)
- Yeh FY, Liu TY, Tseng IH, Yang CW, Lu LC, Lin CS*. 2014. Gold nanoparticles conjugates-amplified aptamer immunosensing screen-printed carbon electrode strips for thrombin detection. Biosensors and Bioelectronics 61:336-343. (IF=6.451, 1/27 in ELECTROCHEMISTRY)
- Yeh FY, Tseng IH, Chuang SH, Lin CS*. 2014. Spacer-enhanced chymotrypsin-activated peptide-functionalized gold nanoparticle probes: a rapid assay for the diagnosis of pancreatitis. RSC Advances 4:22266-22276. (IF=3.708, 38/148 in CHEMISTRY, MULTIDISCIPLINARY)
- Kao CY, Chen TY, Chang YB, Chiu TW, Lin HY, Chen CD, Chang JS, Lin CS*. 2014. Utilization of carbon dioxide in industrial flue gases for the cultivation of microalga Chlorella sp. Bioresource Technology 166:485-493.(IF=5.039, 1/12 in AGRICULTURAL ENGINEERING)
- Huang CH, Chang CC, Kuo CL, Huang CS, Chiu TW, Lin CS*, Liu CS. 2014. Serum iron concentration, but not hemoglobin, correlates with TIMI risk score and 6-month left ventricular performance after primary angioplasty for acute myocardial infarction. Plos ONE 9(8):e104495.(IF=3.534, 8/55 in MULTIDISCIPLINARY SCIENCES)
- Wu HT, Sie SS, Kuan TC, Lin CS*. 2013. Identifying the regulative role of NF-κB binding sites within promoter region of human matrix metalloproteinase 9 (mmp-9) by TNF-α induction. Applied Biochemistry and Biotechnology169(2):438-449. (IF=1.687, 102/165 in BIOTECHNOLOGY & APPLIED MICROBIOLOGY)
- Kuo CE, Liang SF, Lu SS, Kuan TC, Lin CS*. 2013. Estimation and Prediction of Drug Therapy on TheTermination of Atrial Fibrillation by Autoregressive Model with Exogenous Inputs. IEEE Transactions on Information Technology in Biomedicine 17:153-161. (IF=2.072, 22/102 in COMPUTER SCIENCE, INFORMATION SYSTEMS)
- Davis D, Guo X, Musavi L, Lin CS, Chen SH, Wu VCH. 2013. Gold Nanoparticle-Modified Carbon Electrode Biosensor for the Detection of Listeria monocytogenes.Industrial Biotechnology 9:31-36. (non-SCI)
- Cheng KS, Liao YC, Chen MY, Kuan TC, Hong YH, Ko L,Hsieh WY, Chen MR, Lin CS*. 2013. Circulating matrix metalloproteinase-2 and -9 enzyme activities in the children with ventricular septal defect. International Journal of Biological Sciences 9(6):557-563. (IF=4.372, 72/291 inBIOCHEMISTRY & MOLECULAR BIOLOGY)
- Liu CF, Weng SF, Lin YS, Lin CS, Lien CF, Wang JJ. 2013. Increased risk of deep neck infection among HIV-infected patients in the era of highly active antiretroviral therapy – a population-based follow-up study. BMC infectious diseases 13(1):183. (IF=2.561, 35/70 inINFECTIOUS DISEASES)
- Kuan TC, Chen MY, Liao YC, Ko L, Hong YH, Yen CY, Hsieh WY, Cheng KS, Wu CL, Lin CS*. 2013. Angiotensin II downregulates ACE2-mediated enhancement of MMP-2 activity in human cardiofibroblasts. Biochemistry and Cell Biology 91:1-8. (IF=2.350, 182/291 in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Huang CH, Chang CC, Huang CS, Kuo CL, Chen CP, Hsia CH, Chang YM, Chen HT, Feng CC, Lin LS, Yang PT, Tsai CD, Lin CS*, Liu CS. 2013. Using oxidized low-density lipoprotein autoantibodies to predict restenosis after balloon angioplasty in patients with acute myocardial infarction. PlosONE 8(10):e74726. (IF=3.534, 8/55 in MULTIDISCIPLINARY SCIENCES)
- Chuang SH, Chen PH, Chang CM, Lin CS*. 2013. Single-incision vs three-incision laparoscopic cholecystectomy for complicated and uncomplicated acute cholecystitis. World Journal of Gastroenterology 19(43): 7743-7750. (IF=2.348, 36/74 in GASTROENTEROLOGY & HEPATOLOGY)
- Kao CY, Chiu SY, Huang TT, Dai1 L, Wang GH, Tseng CP, Chen CH, Lin CS*. 2012. A mutant strain of microalga Chlorella sp. for the carbon dioxide capture from biogas.Biomass & Bioenergy 36:132-140. (IF=3.411, 2/12 inAGRICULTURAL ENGINEERING)
- Kao CY, Chiu SY, Huang TT, Dai L, Hsu LK, Lin CS*. 2012. Ability of a mutant strain of the microalga Chlorellasp. to capture carbon dioxide for biogas upgrading. Applied Energy 93:176-183. (IF=5.261, 6/133 in ENGINEERING, CHEMICAL)
- Huang CC, Hsu HF, Chen SH, Tsai KY, Huang YT, Lin CS, Hsu SH. 2012. Real-time Detection of α-Thrombin Binding to Single-Strand DNA Aptamers by a Highly Sensitive Si-Based Waveguide SPR Biosensor. Proc. SPIE(Photo-Optical Instrumentation Engineers) 8351: 83512R-83512R-5. (non-SCI)
- Chuang YC, Huang WT, Chiang PH, Tang MC, Lin CS*. 2012. Aqueous zymography screening of matrix metalloproteinase activity and inhibition based on colorimetric gold nanoparticles. Biosensors and Bioelectronics 32:24-31. (IF=6.451, 1/27 inELECTROCHEMISTRY)
- Guo X, Lin CS (contribution as the first author), Chen SH, Ye R, Wu VCH. 2012. A piezoelectic immunosensor for specific capture and enrichment of viable pathogens by quartz crystal microbalance sensor, followed by detection with antibody-functionalized gold nanoparticles. Biosensors and Bioelectronics 38:177-183. (IF=6.451, 1/27 inELECTROCHEMISTRY)
- Chu PT, Lin CS, Chen WJ, Chen CF, Wen HW. 2012. Detection of gliadin in food using a quartz crystal microbalance biosensor that incorporates gold nanoparticles.Journal of Agricultural and Food Chemistry 60:6483-6492.(IF=3.107, 2/56 in AGRICULTURE, MULTIDISCIPLINARY)
- Hsieh WY, Kuan TC, Cheng KS, Liao YC, Chen MY, Lin PH, Hsu YC, Huang CY, Hsu WH, Yu SY, Lin CS*. 2012. ACE/ACE2 ratio and MMP-9 activity as potential biomarkers in tuberculous pleural effusions. International Journal of Biological Sciences 8(8):1197-1205. (IF=4.372, 72/291 in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Chang CC, Hsieh YY, Hsu KH, Lin CS*. 2011. Effects of gonadotropins (Gonal-F and Puregon) on human endometrial cell proliferation in vitro. Taiwanese Journal of Obstetrics and Gynecology 50:42-47. (IF=1.261, 57/78 in OBSTETRICS & GYNECOLOGY)
- Chang CC, Hsieh YY, Hsu KH, Lin CS*. 2011. Effects of aand b recombinant FSH (Gonal-F, Puregon) and progesterone upon human endometrial cell proliferation in-vitro: a preliminary study. Gynecological Endocrinology27:110-116. (IF=1.136, 63/78 in OBSTETRICS & GYNECOLOGY)
- Chang CC, Kuan TC, Hsieh YY, Ho YJ, Sun YL, Lin CS*. 2011. Effects of diosgenin on myometrial matrix metalloproteinase-2 and -9 activity and expression inovariectomized rats. International Journal of Biological Sciences 7:837-847. (IF=4.372, 72/291 in BIOCHEMISTRY & MOLECULAR BIOLOGY)
- Chiu SY, Kao CY, Huang TT, Lin CJ, Ong SC, Chen CD, Chang JS, Lin CS*. 2011. Microalgal biomass production and on-site bioremediation of carbon dioxide, nitrogen oxide and sulfur dioxide from flue gas using Chlorella sp. culture.Bioresource Technology 102:9135-9142. (IF=5.039, 1/12 inAGRICULTURAL ENGINEERING)
- Kuan TC, Yang TH, Wen CH, Chen MY, Lee IL, Lin CS*.2011. Identifying the regulatory element for human angiotensin-converting enzyme 2 (ACE2) expression in human cardiofibroblasts. Peptides 32:1832-1839. (IF=2.614, 103/254 in PHARMACOLOGY & PHARMACY)
- Sun YL, Lin YJ, Lin CS*. 2011. Soluble fusion expression and production of rabbit neutrophil peptide-1 in Escherichia coli. Romanian Biotechnological Letters 16:6618-6629.(IF=0.351, 153/165 in BIOTECHNOLOGY & APPLIED MICROBIOLOGY)
- Ong SC, Kao CY, Chiu SY, Tsai MT, Lin CS*. 2010. Characterization of the thermal-tolerant mutants of Chlorellasp. with high growth rate and application in outdoorphotobioreactor cultivation. Bioresource Technology101:2880-2883. (IF=5.039, 1/12 in AGRICULTURAL ENGINEERING)
- Lin CS*, Pan CH, Wen CH, Yang TH, Kuan TC. 2010. Regulation of angiotensin converting enzyme II by angiotensin peptides in human cardiofibroblasts. Peptides 31:1334-1340. (IF=2.614, 103/254 in PHARMACOLOGY & PHARMACY)
- Lin LM, Lai LP, Lin CS*, Chou NK, Chiu CY, Lin JL. 2010. Left ventricular extracellular matrix remodeling in dogs with right ventricular apical pacing. Journal of Cardiovascular Electrophysiology 21:1142-1149. (IF=2.881, 48/125 inCARDIAC & CARDIOVASCULAR SYSTEMS)
- Sun YL, Kuan TC, Lin YJ, Chou YC, Lin CS*. 2010. Construction and expression of rabbit neutrophil peptide-1 gene in Escherichia coli. Annals of Microbiology 60:329-334. (IF=1.039, 129/165 in BIOTECHNOLOGY & APPLIED MICROBIOLOGY)
- Chang CC, Hsieh YY, Lin WH, Lin CS*. 2010. Leiomyoma and vascular endothelial growth factor gene polymorphisms: a systematic review. Taiwanese Journal of Obstetrics andGynecology 49:247-253. (IF=1.261, 57/78 in OBSTETRICS & GYNECOLOGY)
- Chang CC, Hsieh YY, Hsu KH, Tsai HD, Lin WH, Lin CS*. 2010. Deleterious effects of arsenic, benomyl and Carbendazim on human endometrial cell proliferation in vitro. Taiwanese Journal of Obstetrics and Gynecology49:449-454. (IF=1.261, 57/78 in OBSTETRICS & GYNECOLOGY)
- Chuang YC, Li JC, Chen SH, Liu YU, Kuo CH, Huang WT,Lin CS*. 2010. An optical biosensing platform for proteinase activity using gold nanoparticles. Biomaterials31:6087-6095. (IF=8.312, 2/77 in ENGINEERING, BIOMEDICAL)
- Chen SH, Chuang YC, Lu YC, Lin HC, Yang YL, Lin CS*. 2009. A method of layer-by-layer gold nanoparticles hybridization in a quartz crystal microbalance DNA sensing system used to detect dengue virus. Nanotechnology20:215501. (IF=3.644, 30/222 in MATERIALS SCIENCE, MULTIDISCIPLINARY)
- Chen SH, Lin KI, Tang CY, Peng SL, Chuang YC, Lin YR, Wang JP, Lin CS*. 2009. Optical detection of human papillomavirus type 16 and type 18 by the sequence sandwich hybridization with oligonucleotide-functionalized Au nanoparticles. IEEE Transactions on NanoBioscience8:120-131. (IF=1.712, 37/63 in NANOSCIENCE & NANOTECHNOLOGY)
- Chiu SY, Tsai MT, Kao CY, Ong SC, Lin CS*. 2009. The air-lift photobioreactors with flow patterning for a high-density culture of microalgae and carbon dioxide removal.Engineering in Life Sciences 9:254-260. (IF=1.504, 101/160 in BIOTECHNOLOGY & APPLIED MICROBIOLOGY)
- Chang CC, Hsieh YY, Wang YK, Hsu KH, Tsai HD, Tsai FJ, Lin CS*. 2009. Identification of novel peptides specifically binding to endometriosis by screening phage-displaying peptide libraries. Accepted by Fertility and Sterility 92:1850-1855. (IF=3.122, 10/75 in OBSTETRICS & GYNECOLOGY)
- Chiu SY, Kao CY, Tsai MT, Ong CS, Chen CH, Lin CS*. 2009. Lipid accumulation and CO2 utilization ofNannochloropsis oculata in response to CO2 aeration.Bioresource Technology 100:833-838. (IF=4.365, 1/12 inAGRICULTURAL ENGINEERING)
- Wu VCH, Qiu X, de los Reyes BG, Lin CS, Pan Y. 2009.Application of cranberry concentrate (Vacciniummacrocarpon) to control Escherichia coli O157:H7 inground beef and its antimicrobial mechanism related to thedownregulated slp, hdeA and cfa. Food Microbiology 26:32-38. (IF=3.320, 6/126 in FOOD SCIENCE & TECHNOLOGY)
- Chen CL, Huang SKS, Lin JL, Lai LP, Lai SC, Liu CW, Chen WC, Wen CH, Lin CS*. 2008. Upregulation of matrix metalloproteinase-9 and tissue inhibitors ofmetalloproteinases in rapid atrial pacing-induced atrial fibrillation. Journal of Molecular and Cellular Cardiology45:742-753. (IF=5.499, 12/114 in CARDIAC & CARDIOVASCULAR SYSTEMS)
- Tsai CT, Lin JL, Lai LP, Lin CS, Huang SKS. 2008. Membrane translocation of small GTPase Rac1 and activation of STAT1 and STAT3 in pacing-induced sustained atrial fibrillation. Heart Rhythm 5:1285-1293.(IF=4.246, 23/114 in CARDIAC & CARDIOVASCULAR SYSTEMS)
- Lin YH, Chen SH, Chuang YC, Lu YC, Shen TY, Chang CA, Lin CS*. 2008. Disposable amperometricimmunosensing strips fabricated by Au nanoparticles-modified screen-printed carbon electrodes for the detection of foodborne pathogen Escherichia coli O157:H7.Biosensors and Bioelectronics 23:1832-1837. (IF=5.361, 1/26 in ELECTROCHEMISTRY)
- Lin CS*, Pan CH. 2008. Regulatory mechanisms of atrial fibrotic remodeling in atrial fibrillation. Cellular and Molecular Life Sciences 65:1489-1508. (IF=7.047, 35/286 inBIOCHEMISTRY & MOLECULAR BIOLOGY)
- Yen CH, Yang CK, Chen IC, Lin YS, Lin CS, Chu S, TuCF. 2008. Expression of recombinant Hirudin in transgenic mice milk driven by the goat b-casein promoter.Biotechnology Journal 3:1067–1077. (non-SCI)
- Chen SH, Wu VCH, Chuang YC, Lin CS*. 2008. Using oligonucleotide-functionalized Au nanoparticles to rapidly detect foodborne pathogens on a piezoelectric biosensor.Journal of Microbiological Methods 73:7-17. (IF=2.018, 41/71 in BIOCHEMICAL RESEARCH METHODS)
- Sun YL, Chou YC, Kuan TC, Lin CS*. 2008. Expression of recombinant anticoagulant hirudin in the differentiated cultures of porcine mammary epithelial cell line SI-PMEC.Cell Biology International 32:739-747. (IF=1.747, 141/177 in CELL BIOLOGY)
- Pan CH, Wen CH, Lin CS*. 2008. Interplay of angiotensin II and angiotensin 1-7 in the regulations of matrixmetalloproteinases of human cardiocytes. Experimental Physiology 93:599-612. (IF=3.333, 22/77 in PHYSIOLOGY)
- Chiu SY, Kuan TC, Kao CY, Ong SC, Chen CH, Lin CS*. 2008. Reduction of CO2 by a high-density culture ofChlorella sp. in a semicontinuous photobioreactor.Bioresource Technology 99:3389-3396. (IF=4.365, 1/12 inAGRICULTURAL ENGINEERING)
- Su CH, Hsieh BT, Leung SW, Wu CJ, Chiu SY, Lin CS*. 2007. Increased expression of nuclear NF-kB after coronary artery balloon injury can be inhibited by intracoronary beta-irradiation. International Journal of Radiation Biology83:707-716.
- Lin CS, Lai LP, Lin JL, Sun YL, Hsu CW, Chen CL, Mao SJT, Huang SKS. 2007. Increased expression of extracellular matrix proteins in rapid atrial pacing-induced atrial fibrillation. Heart Rhythm 4:938-949.
- Yen NT, Lin CS, Ju CC, Wang SC, Huang MC. 2007. Mitochondrial DNA polymorphism and determination of effects on reproductive trait in pigs. Reproduction in Domestic Animals 42:387-392.
- Lin CS*, Kuo CL, Wang JP, Cheng JS, Huang ZW, Chen CF. 2007. Growth inhibitory and apoptosis inducing effect of Perilla frutescens extract on human hepatoma HepG2 cells. Journal of Ethnopharmacology 112:557-567.
- Wu VCH, Chen SH, Lin CS*. 2007. Real-time detection ofEscherichia coli O157:H7 sequences using a circulating-flow system of quartz crystal microbalance. Biosensors and Bioelectronics 22:2967-2975.
- Pan CH, Lin JL, Lai LP, Chen CL, Huang SKS, Lin CS*. 2007. Downregulation of angiotensin converting enzyme II is associated with pacing-induced sustained atrial fibrillation. FEBS Letters 581:526-534.
- Chen CL, Lin JL, Lai LP, Pan CH, Huang SKS, Lin CS*. 2007. Altered expression of FHL1, CARP, TSC-22 and P311 provide insights into complex transcriptional regulation in pacing-induced atrial fibrillation. Biochimica etBiophysica Acta 1772:317-329.
- Hsieh YY, Wang YK, Tsai HD, Yang TC, Yeh LS, Lin CS*. 2007. Angiotensin I-converting enzyme insertion-related genotypes and allele are associated with higher susceptibility of endometriosis and leiomyoma. Molecular Reproduction and Development 74:808-814.
- Hsieh YY, Wang JP, Lin CS*. 2007. Four novel single nucleotide polymorphisms within the promoter region of p53 gene and their associations with uterine leiomyoma.Molecular Reproduction and Development 74:815-820.
- Hsieh YY, Wang YK, Chang CC, Lin CS*. 2007. Estrogen receptor alpha -351 XbaI*G and -397 PvuII*C-related genotypes and alleles are associated with higher susceptibilities of endometriosis and leiomyoma. Molecular Human Reproduction 13:117-122.
- Hsieh YY, Lin CS*. 2006. P53 codon 11, 72, and 248 gene polymorphisms in endometriosis. International Journal of Biological Sciences 2:188-193.
- Hsieh YY, Chang CC, Lin CS*. 2006. Seminalmalondialdehyde concentration but not glutathione peroxidase activity is negatively correlated with seminal concentration and motility. International Journal of Biological Sciences 2:23-29.
- Sun YL, Lin CS, Chou YC. 2006. Establishment and characterization of a spontaneously immortalized porcine mammary epithelial cell line. Cell Biology International30:970-976.
- Hsieh YY, Chan IP, Wang HI, Chang CC, Huang CW, Lin CS*. 2005. PROGINS Alu sequence insertion is associated with hyperprolactinaemia but not leiomyoma susceptibility.Clinical Endocrinology 62:492-497.
- Lin CS*, Hsu CW. 2005. Differentially transcribed genes in skeletal muscle of Duroc and Taoyuan pigs. Journal of Animal Science 83:2075-2086.
- Sun YL, Lin CS, Chou YC. 2005. Gene transfection and expression of the primary culture of mammary epithelial cells isolated from lactating sows. Cell Biology International29:576-582.
- Hsieh YY, Chang CC, Tsai HD, Lin CS*. 2005. Leukemia inhibitory factor in follicular fluid is not related with the number and quality of embryos as well as implantation and pregnancy rates. Biochemical Genetics 43:502-506.
- Lai LP, Lin JL, Lin CS, Yeh HM, Tsay YG, Lee CF, Lee HH, Chang ZF, Hwang JJ, Su MJ, Tseng YZ, Huang SKS. 2004. Functional genomic study on atrial fibrillation using cDNA microarray and two-dimensional protein electrophoresis techniques and identification of the myosin regulatory light chain isoform reprogramming in atrial fibrillation. Journal of Cardiovascular Electrophysiology15:214-223.
- Lin CC, Lin JL, Lin CS, Tsai MC, Su MJ, Lai LP, Huang SKS. 2004. Activation of the Calcineurin-Nuclear Factor of Activated T-Cell Signal Transduction Pathway in Atrial Fibrillation. Chest 126:1926-1932.
- Hsieh YY, Chang CC, Hsu CW, Lin CS*. 2004. Gene transfections with p53 and p21 inhibits cell proliferation, collagen type I, leukemia inhibitory factor, and tumor necrosis factor alpha expressions of leiomyoma cells.Fertility and Sterility 81:1665-1670.
- Sun YL and Lin CS*. 2003. Establishment and application of a fluorescent PCR-RFLP method for identifying of porcine, caprine, and bovine meats. Journal of Agricultural Food and Chemistry 51:1771-1776.
- Lin JL, Lai LP, Lin CS, Du CC, Wu TJ, Chen SP, Lee WC, Yang PC, Tseng YZ, Lien WP, Huang SWS. 2003. Electrophysiological mapping and histological examinations of the swine atrium with sustained (³ 24 hours) atrial fibrillation: a suitable animal model for studying human atrial fibrillation. Cardiology 99:78-84.
- Lin CS*. 2003. Effects of Freshwater Clam Extract on Liver Functions in Alcoholic Liver Injury. Nutritional Sciences Journal 28:26-33. (In Chinese)
- Wu HT, Lin CS, Huang MC. 2003. In vitro and ex vivo GFP expression in alveolar mammary epithelial cells and mammary glands driven by the distal 5’ regulative sequence and intron 1 of goat b-casein gene. Reproduction, Fertility, Development 15:1-9.
- Lin CS, Sun YL and Liu CY. 2003. Cardiac mitochondrial dysfunction and mitochondrial DNA depletion in pigs with hypertrophic cardiomyopathy. Research in Veterinary Science 74:219-226.
- Chen CF and Lin CS*. 2003. Hepatoprotective Effects of Clam Extract Supplementation on Subacute Hepatitis Induced by Carbon Tetrachloride in Rats. Taiwanese Journal of Agricultural Chemistry and Food Technology41:159-166. (In Chinese)
- Wu ST, Chou CK, Lin CS and Huang MC. 2003. Effects of glucose concentration on in vitro fertilization in BALB/c mice. Reproduction Domestic Animal 38:1-5.
- Lin CS, Wu YC, Sun YL and Huang MC. 2002. Postnatal Expression of Growth/Differentiation Factor-8 (GDF-8) Gene in European and Asian Pigs. Asian-Australia Journal of Animal Science 9:1244-1249.
- Hsieh YY, Sun YL, Chang CC, Lee YS, Tsai HD and Lin CS*. 2002. Superoxide dismutase activities of spermatozoa and seminal plasma are not correlated with male infertility.Journal of Clinical Laboratory Analysis 16:127-131.
- Hsieh YY, Lin CS, Sun YL, Chang CC, Tsai HD and Wu JCH. 2002. In vivo gene transfer of leukemia inhibitory factor into mouse endometrium. Journal of Assisted Reproduction and Genetics 19:79-83.
- King YT, Lin CS, Lin JH, Lee WC. 2002. Whole-body hyperthermia-induced thermotolerance is associated with the induction of Heat Shock Protein 70 in mice. Journal of Experimental Biology 205:273-278.
- Wu CH, Lin CS, Hung JS, Wu CJ, Lo PH, Jin G, Shyy YJ, Mao SJ, Chien S. 2001. Inhibition of neointimal formation in porcine coronary artery by a Ras mutant. Journal of Surgical Research 99:100-106.
- Sun YL, PP Tsai, PC Yang, PH Lin, SL Chen, SK Liu andCS Lin*. 2000. The plasma and myocardial lactate dehydrogenase activities in the pig with hypertrophic cardiomyopathy: evidence for myocardial damage by cardiac enzyme determination. Journal of the Chinese Society Veterinary Science 26:56-62. (In Chinese)
- Sun YL, JCH Wu, SJT Mao, PH Lin, SL Chen, PC Yang and CS Lin*. 2000. Efficiencies of porcine vascular smooth muscle cells and arterial gene transfer and expression mediated by recombinant adenovirus. Journal of the Chinese Society of Animal Science 29:179-190. (In Chinese)
- Lin CS*, Sun YL, Lu CY, Chang LC, Cheng IC, Yang PC, Mao JST and Huang MC. 1999. Complete nucleotide sequence of pig (Sus scrofa) mitochondrial genome and dating evolutionary divergence within Artiodactyla. Gene236:107-114.
- Lin CS*, CY Liu, HT Wu, YL Sun, LC Chang, NT Yen, PC Yang, MC Huang and SJT. Mao. 1998. SSCP Analysis in the D-loop region of porcine mitochondrial DNA as confirmed by sequence diversity. Journal of Animal Breeding and Genetics 115:73-78. (SCI)
- Lin CS*, HT Wu, CY Liu, YL Sun, LC Chang, CC Hong, PC Yang, SJT Mao and MC Huang. 1997. Amplifying the D-loop region of mitochondrial DNA from whole blood and embryonic cells of mammalian animals. Journal of the Agricultural Association of China. 180:80-91. (In Chinese)
- Lin CS, CY Liu, YL Sun, LC Chang, YT Chiu, SY Huang, JH Lin, PC Yang, R Chu, MC Huang and SJT Mao. 1997. Alteration of endogenous antioxidant enzymes in naturally occurring hypertrophic cardiomyopathy. Biochemistry Molecular & Biology International 43(6):1253-1263.
- Lin CS, Kuo CM, Yang YC, Zhang WX. Continuous microalgae culture module and method of culturing microalgae having macular pigment. IPA-ROC: I682032 (專利權期間:2020/01/11~2038/06/12)
- Lin CS, Kao CY, Chen TY, Chang YB, Chiu SY. The technique of magnetic particles applied to microalgae harvest. IPA-ROC: I615467 (專利權期間:2018/02/21~2033/12/29)
- Lin CS, Cheng JS, Kuo CM, Lin TH. Alkali resistant Chlorella sp. and method for reducing and recycling CO2. IPA-ROC: I614019 (專利權期間:2018/02/11~2037/07/05)
- Tseng CP, Chen CC, Lin CS. Biogas electric generator and electricity generation method using microalgae carbon capture. IPA-ROC: I555840 (專利權期間:2016/11~2032/03)
- Lin CS, Kao CY. Microalgae cultivation module including circular tube-shaped cultivation bag. IPA-ROC: I457073 (利權期間:2014/10/21~ 2032/7/18)
- Cheng JS, Lin CS, Chen CY, Kao CY. Carbon dioxide-capturing apparatus for microalgae cultivation and the method thereof. IPA-ROC: I479988 (專利權期間:2015/4/11~ 2032/8/27; 交大與成大共擁專利所有權)
- Lin CS, Chiu SY, Kao CY. Microalgae cultivation module. IPA-ROC I433647 (專利權期間:2014/4/11~ 2031/9/5
日期 | 技術名稱 | 專利名稱 | 授權單位 | 被授權單位 |
---|---|---|---|---|
2011/8~2012/7 | 微藻光生物反應器模組 | 一種用於減碳與產製生物質之微藻養殖模組 | 國立交通大學、國立成功大學 | 中國鋼鐵股份有限公司 |
1996/8~2001/7 | 動物粒線體DNA分離組劑 | 利用特定比重溶液離心法快速分離動物粒線體DNA | 台灣養豬科學研究所 | 波仕特股份有限公司 |
Period | Plan Name |
---|---|
2018/08/01-2021/07/31 | Constructing a two-stage system for microalgal cultivation to efficiently produce macular pigment of microalgae and the biological function evaluation of microalgal macular pigment products |
2017/08/01-2018/07/31 | Development and applications of the functional animal feed additive based on microalgae biomass |
2017/01/01-2017/12/31 | Developing commercialization technology for high-value CO2 utilization using algae-based CO2 fixation and biorefinery platform |
2016/01/01-2016/12/31 | Eveloping CO2-Reutilization Core Technologies for the Conversion of Biofuels and Chemicals. (3/3) |
2015/08/01-2018/07/31 | The use of renin-angiotensin-aldosterone system blockade in improving acute kidney injury. |
2015/08/01-2018/07/31 | Studying the effects of regulating renin-angiotensin system on the pathogenesis of diabetic nephropathy using the mice with db/db and ACE2 double gene knockout. |
2015/01/01-2015/12/31 | eveloping CO2-Reutilization Core Technologies for the Conversion of Biofuels and Chemicals. (2/3) |
2014/04/01-2014/12/31 | Developing CO2-Reutilization Core Technologies for the Conversion of Biofuels and Chemicals. (1/3) |
2013/02/01-2013/12/31 | Microalgae Biofuels – Developing Bridging Technologies toward Commercialization. |
2012/08/01-2015/07/31 | Studying the regulatory elements of angiotensin converting enzyme II (ACE2) and the molecular mechanism of ACE2 regulation on pulmonary fibrosis by experimental mouse models. |
2012/08/01-2015/07/31 | Investigation of Mango Allergy in Taiwan, and the Production of Recombinant Mango Major Allergen (Man i1) with Its Polyclonal and Monoclonal Antibodies for Developing a Rapid Lateral Flow Assay to Detect Mango Allergens. |
2012/01/01-2012/12/31 | Development the Technology of Agricultural Waste Bioconversion to Biogas for Electricity Generation and Carbon Dioxide Elimination by Microalgae. (3/3) |
2012/01/01-2013/02/28 | Development of Integrated Technology for Microalgal Bioenergy Production. (2/2)2011/01/01-2011/12/31 |
2011/08/01-2013/07/31 | Design and Fabrication of Si-Based High-Sensitivity Novel Waveguide Surface Plasmon Resonance (Spr) Chips with Flow Channels for Dengue VI Rus and Protein Kinase Activity Sensing. |
2011/01/01-2011/12/31 | Development the Technology of Agricultural Waste Bioconversion to Biogas for Electricity Generation and Carbon Dioxide Elimination by Microalgae. (2/3) |
2009/11/01-2010/12/31 | Development of Integrated Technology for Microalgal Bioenergy Production. (1/2) |
2009/08/01-2012/07/31 | Studying the roles of angiotensin converting enzyme II –angiotensin 1-7 (ACE2–Ang 1-7) axis in the disease process of heart failure. |
2009/08/01-2012/07/31 | Development of Three Rapid Assays for the Detection of Wheat Allergens in Foods by the Use of Liposomal Nanovesicles- Highly Sensitive Quartz Crystal Microbalance Assay, Highly Specific Immunomagnetic Bead Assay, and Immunolateral Flow Assay. |
一、生物科技技術與應用之研發演進。
二、專利分析概論。
1. 專利與專利分析之重要性。
2. 專利要件與專利案之撰寫。
3. 專利與專利資訊之檢索。
三、生技為題之中華民國專利之撰寫。每兩位學生進行同一主題報告之撰寫。
四、生物科技(以基因晶片為例)之專利檢索與解讀。
五、專利管理地圖與技術地圖製作之案例解讀。
1. 人工血管及人工瓣膜專利管理地圖的製作及分析。
2. 應用膠原蛋白於人工皮膚及創傷敷料之專利技術趨勢分析。
3. 由專利技術趨勢探討未來利用基因轉殖動物乳腺組織生產醫藥用蛋白質之發展。
4. 生物晶片之專利趨勢分析:解析微陣列基因晶片之專利技術趨勢。
5. 血糖監視系統專利趨勢與技術分析。
6. 食藥用菇類專利趨勢分析。
7. 血管藥物塗層支架之專利趨勢分析。
六、製作生物科技之專利管理地圖。每三至四位學生進行同一主題之分析,以超過500個專利案為限。
七、製作生物科技之專利技術地圖。每三至四位學生進行同一主題之分析,以超過100個專利案為限。
八、生物科技之專利管理地圖與技術地圖分析報告之撰寫。每三至四位學生進行同一主題報告之撰寫。
生理學 Physiology(與曲在雯、鄒協成、王志宏等教師共同合授)
- 大學部生理學為4學分(上、下學期各2學分),研究所生理學為3學分。
- 教導學生人體正常生理機能的基本原理和一些常見疾病之病徵和生理機轉。由於本課程屬基礎生理學課程,研究生基本上以大學時期未修研過生理學者為宜。
- 以Human Physiology (by Stuart Ira Fox, McGraw-Hill Companies)內容為基本教材。
- 教授指導”Blood, Heart and Circulation”、” Cardiac Output, Blood Flow, and Blood Pressure”、”Endocrine Glands”及” Respiratory Physiology”等四部分。
- 上課方式:以PPT講義之講述為主,佐以一些簡易可於教室中施行的生理檢測實驗,例如血糖、血氧、ECG、血壓、呼吸…等等。
- 成績評量方式:期中與期末考試(考題包括選擇、選填及簡答題),上課參與討論極為重要,是加分重要方法。
專題討論-生物醫學組 Seminar of Biomedicine
課程目標
以生物醫學研究或跨領域生物醫學為主軸,教導學生如何閱讀、討論、準備及報告科學研究報告。
課程綱要
- 探討近代生物醫學的科學研究熱門重點。
- 以生物醫學研究為題之專業報告準備。
- 生物醫學之科學期刊報告研讀 (以Nature Medicine、Nature、Science為主)。
- 每位學生進行一生物醫學相關研究之科學期刊報告。
- 學生須做兩次report,一次為25 min,一次5 min。兩次report的Journal一樣,不過後者要精簡些。5 min的report會錄音。
課程評分標準
- 上課出席並參與討論情形 50%。
- 專題報告 50%。
上課相關事宜
- 學生報告時應視為參加正式科學研討會,故須著正式服裝,並遵照其報告規範。
- 學期結束,學生會收到上課所有人之report journal和slides。學生同時會收到自己report的錄音檔。
課程綱要
應氣候與生態環境的變遷、人口結構的改變、全球貿易自由化及食品安全意識抬頭,新農業成為新世代生物科技重要一環。本課程將教授本系研究生了解新農業創新科技與產業的發展,此可強化研究生在此領域的學能,增加其未來進入此一新興產業的機會。新農業範疇包括生物經濟、循環農業、智慧農業、綠能、食品加值及食品安全科技等創新加值農業。而本課程內容包括動(含水產)、植物農業與食品科技之創新關鍵科技的發展和應用,以及其近年來創新農業產業的發展。
課程單元主題
- 新農業與生物經濟
- 新農業的創新科技
- 新農業的創新產業
- 新農業創新產業參訪
- 專題報告